Clinical Research Project Manager B/C
- Location
- Presbyterian Medical Center
- Work mode
- On-site
- Employment type
- Full-time
About the job
University Overview The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Large Employers in 2023.
Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.
The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.
Posted Job Title Clinical Research Project Manager B/C
Job Profile Title Clinical Research Project Manager B
Job Description Summary Clinical Research Project Manager B The Project Manager B will provide advanced project management and operational expertise in support of clinical research studies conducted within the Cardiovascular Division of PPMC. PM B position provides independent oversight of study operations, including project planning, team management, and study execution.
The Project Manager B will serve as the primary project manager for assigned studies, with accountability for study execution, operational planning, and overall performance including enrollment. This role will coordinate complex study activities across multidisciplinary teams including investigators, coordinators, core labs, and external collaborators. The Project Manager B will ensure studies are conducted in accordance with protocol requirements, sponsor expectations, and all applicable regulatory and institutional guidelines.
Responsible for assisting with study coordination and recruitment for industry sponsored studies. Works directly with study physicians, research director and other research staff. Performs screening visits, consenting of participants, entering data into databases. Coordinate several investigational trials within the cardiovascular division of PPMC, instruct and support investigators and study staff on carrying out clinical protocol and other study related requirements
Responsibilities include developing and maintaining detailed project plans and timelines, overseeing recruitment and enrollment strategies, and ensuring adherence to study milestones. PM B will lead track progress and proactively identify and resolve operational challenges. This individual will oversee compliance reviews and will ensure audit and inspection readiness across assigned studies. PM B will supervise and mentor research staff, and will provide guidance on day-to-day study operations, workload prioritization, and performance expectations. This role will promote consistency in processes, tools, and documentation, and contribute to the development and implementation of best practices and standard operating procedures. In collaboration with PPMC Administrative Director, the Project Manager B will obtain detailed knowledge of all components of trial protocols screening and enrolling patients, conducting follow-up activities, abstracting medical and demographics data from medical records, completing source documents and case report forms, data entry using various electronic data collection systems, managing the adverse event reporting process. The Project Manager B functions with a high degree of independence in managing assigned projects but escalates strategic decisions and high-level study direction to senior leadership (e.g., Administrative Director, etc.).
Clinical Research Project Manager C The Project Manager C will support the PPMC Cardiovascular Research and be responsible for day-to-day operations of multiple clinical research projects. The Research Project Manager will take leadership role in developing study documents managing the detailed operations of projects, coordinating activities in multiple studies, quality control and will lead project strategy. PM C will be required to ensure that studies/research are conducted safely and according to protocol, provide supervision to the teams conducting the study/interventions and collaborates with the funding agencies..
The Project Manager C will serve as the primary project manager for assigned studies, with accountability for study execution, operational planning, and overall performance including enrollment. This role will coordinate complex study activities across multidisciplinary teams including investigators, coordinators, core labs, and external collaborators.
This is a leadership position and will involve hiring, onboarding and oversee the detailed operations of clinical research activities including recruitment, conducting research visits, data entry. Coordinate investigational trials within the cardiovascular division of PPMC, instruct and support investigators and study staff on carrying out clinical protocol and other study related requirements
PM C will lead track progress and proactively identify and resolve operational challenges. This individual will oversee compliance reviews and will ensure audit and inspection readiness across assigned studies. PM C will supervise and mentor research staff, and will provide guidance on day-to-day study operations, workload prioritization, and performance expectations. This role will promote consistency in processes, tools, and documentation, and contribute to the development and implementation of best practices and standard operating procedures.
The Project Manager C functions with a high degree of independence in managing assigned projects but escalates strategic decisions and high-level study direction to senior leadership (e.g., Administrative Director, etc.).
Job Description This position is contingent upon favorable funding. Clinical Research Project Manager B Job Responsibilities
- Independently manage complex, multi-site cardiovascular clinical research studies in collaboration with the Principal Investigator, including daily operations, study coordination, recruitment/enrollment oversight, and troubleshooting in accordance with Good Clinical Practice (GCP) and all applicable regulatory requirements.
- Supervise, manage, and mentor study teams including onboarding, training, workload management, and performance oversight; develop and drive study timelines, recruitment strategies, and operational plans.
- Assist in research studies using approved protocols, according to GCP. Familiarize with all components of study protocols by review of study. Attend Investigators Meetings. Assure accurate, completion and updates of the Delegation of Duties and Authorized Signatures Form. Confer with the pharmacist as needed to assure the availability of study drug. Create, maintain research data, regulatory files.
- Timely initiation of screening, enrolling patients. Screen to identify potential patients for specific studies, determine patient eligibility by communicating with physicians, clinical staff and by reviewing medical records to validate potential patient data against Inclusion /Exclusion checklists. Recruit patients, explain protocol, consent forms. Assure original signed consents are maintained in the study binder. Complete screening/enrollment logs and submit to sponsor, as protocol.
- Complete all source documents and worksheets. Complete and/or enter all clinical record forms (CRFs). Create and maintain subject binders. Obtain records required to complete CRFs. Assure inclusion of enrollment information, research orders, and other communications are entered into the electronic medical record of each subject. Resolve data queries with sponsors/CROs.
- Support multicenter coordination and external collaborations, including communication with partner sites, core labs, and external stakeholders as applicable.
- Recruiting, training, and supervising full time research staff.
- Develop/ Help create EPIC Smart phrases.
Qualifications
- Bachelor's Degree with 5-7 years of related experience or equivalent combination of education and experience is required. Master's degree and 3-5 years of experience preferred.
Clinical Research Project Manager C Job Responsibilities
- Staff supervision: Assist and train direct and/or indirect research staff on procedures as required per protocol(s). Includes onboarding and training, data and lab management, protocol compliance and QC/QA, human subjects protection and GCP, and project assignments/staff mentoring/biannual performance appraisal completion.
- Independently manage complex, multi-site cardiovascular clinical research studies in collaboration with the Principal Investigator, including daily operations, study coordination, recruitment/enrollment oversight, and troubleshooting in accordance with Good Clinical Practice (GCP) and all applicable regulatory.
- Assist in research studies using approved protocols, according to GCP. Familiarize with all components of study protocols by review of study. Attend Investigators Meetings. Assure accurate, completion and updates of the Delegation of Duties and Authorized Signatures Form. Confer with the pharmacist as needed to assure the availability of study drug. Create, maintain research data, regulatory files.
- Timely initiation of screening, enrolling patients. Screen to identify potential patients for specific studies, determine patient eligibility by communicating with physicians, clinical staff and by reviewing medical records to validate potential patient data against Inclusion /Exclusion checklists. Recruit patients, explain protocol, consent forms. Assure original signed consents are maintained in the study binder. Complete screening/enrollment logs and submit to sponsor, as protocol.
- Complete all source documents and worksheets. Complete and/or enter all clinical record forms (CRFs). Create and maintain subject binders. Obtain records required to complete CRFs. Assure inclusion of enrollment information, research orders, and other communications are entered into the electronic medical record of each subject. Resolve data queries with sponsors/CROs.
- Support multicenter coordination and external collaborations, including communication with partner sites, core labs, and external stakeholders as applicable.
- Recruiting, training, and supervising full time research staff.
- Develop/ Help create EPIC Smart phrases.
Qualifications
- Bachelor's degree and 7-10 years of related experience or equivalent combination of education and experience is required. Master's degree and 5-7 years of experience preferred.
Job Location - City, State Philadelphia, Pennsylvania
Department / School Perelman School of Medicine
Pay Range $75,804.00 - $106,940.00 Annual Rate Salary offers are made based on the candidate’s qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job’s level. Internal organization and peer data at Penn are also considered.
Equal Opportunity Statement The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic
From Trustees of University of Pennsylvania's careers page (Workday), checked 5 Nov 2026.
How to apply
- Select Apply on upenn.wd1.myworkdayjobs.com. It opens Trustees of University of Pennsylvania's own application form in a new tab, run on Workday.
- Fill in the form and upload your résumé there. Jobiwork never sees your application.
- Trustees of University of Pennsylvania will reply to you directly. No real employer asks you for money to apply.
Posted 4 Nov 2026 · checked 5 Nov 2026 · Report this job